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Family Forum / Parenting / Parenting / May 2008



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DS got the Hives!

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meatnub - 27 May 2008 14:59 GMT
Well for those of you living in the states, I hope your Memorial Day
weekend went better than ours!

My son had an ear infection last week and we were treating it with
Amoxicyllin (sp?). He's had the antibiotic 2 times previously. He was
on it for about 6 days, then friday morning when I went to change him
out of his jammies, he's covered in red splotches and some bumps as
well in the splotches.

We take him to the ped and they say its most likely a reaction to the
Amoxicyllin. We say he was on it before but the ped says that he can
just start having an allergic reaction to it as he grows.

So the ped checks his ears, and the ear we were treating is fine now,
but now his other ear & tube are clogged and we need to start treating
that for infection. So she takes him off the Amoxi and puts him on
Prelone I believe....

Ped says to give him benadryl every 6 hours to help reduce the hives.

So we head out of town to visit my folks as planned, thinking
everything will be fine. The next morning he's got a whole lot more of
them, and his eyes are puffy, like he was in a boxing match. Red
splotches all over his face.

We take him to the hospital and they pretty much come to the same
conclusion that it's an allergic reaction. They give him a breathing
treatment and put him on a steroid (forget the name off hand) for 3
days, and once we started giving him that it immediately started to
reduce the hives.

They said the hives can last up to 72 hours. Well today I'm glad to
say they are all gone and he's doing much better.

Don't really know if it was the Amoxicyllin.. but I would have to
assume so.

Anyone else ever experience this?

I wish our Ped would have prescribed the steroid first, but I guess
that's a last ditch alternative.

But our DS was a trooper. Though the benadryl kept him sleepy a lot
during the weekend he never had a fever and was happy and playful.

Paul
meatnub - 27 May 2008 15:05 GMT
Also.. DW and I are not allergic to any medications, but DW's mother
is. So we're wondering if perhaps his allergic reaction to Amoxicillin
skipped a generation? Of course, if it was the Amoxicillin he was
reacting to.

We don't think he's allergic to cow's milk, he's still drinking it
today and like I said the hives are gone, and had the milk 2 weeks
prior with no reactions.

He had peanut butter a couple days before the hives, but it was only
about a tablespoon's worth, if that, and again, he had some a week
prior.

So I guess we just stop giving him Amoxicillin? How do we know that's
what it was?
MarieD - 27 May 2008 15:14 GMT
> Also.. DW and I are not allergic to any medications, but DW's mother
> is. So we're wondering if perhaps his allergic reaction to Amoxicillin
[quoted text clipped - 11 lines]
> So I guess we just stop giving him Amoxicillin? How do we know that's
> what it was?

My two older daughters both had a reaction to Amoxicillin (hives, actually).
My brother is allergic to penicillin but I'm not. My oldest was right at a
year old when she had hers, and the next child was quite older, maybe 7 or 8
years old, but she hadn't had antibiotics much in her life at all.
Marie
Banty - 27 May 2008 15:23 GMT
>Also.. DW and I are not allergic to any medications, but DW's mother
>is. So we're wondering if perhaps his allergic reaction to Amoxicillin
[quoted text clipped - 11 lines]
>So I guess we just stop giving him Amoxicillin? How do we know that's
>what it was?

Get thee to a pediatric allergist who can perform a rast test to see what
exactly he is allergic to.  And who can educate you more on allergic reactions
in general.

Allergies do run in famillies; I don't think the pattern of inheritance is
simple enough to say who he may have inherited a propensity for allergies from.

A trait can "skip a generation" only if it's a autosomal recessive and you
happen to be someone with the same recessive gene.  But I don't think allergies
are so simple as that.  It's a complex interaction between an inherited
propensity and environmental exposures as far as I understand it.

It's not the end of the world - it's something to be managed.  Amoxicillin is a
penicillin, and allergic reactions to penicillin are common.  You really do need
to follow up and find out if it is that, or something else.  An anaphylactic
reaction can be deadly.

Banty
Rosalie B. - 27 May 2008 16:12 GMT
>>Also.. DW and I are not allergic to any medications, but DW's mother
>>is. So we're wondering if perhaps his allergic reaction to Amoxicillin
[quoted text clipped - 4 lines]
>>today and like I said the hives are gone, and had the milk 2 weeks
>>prior with no reactions.

The classic allergic response is to have no reaction the first or
second time of exposure and then a gap in exposure.  Then the next
time the allergen is presented, there is a bad reaction.

>>He had peanut butter a couple days before the hives, but it was only
>>about a tablespoon's worth, if that, and again, he had some a week
[quoted text clipped - 21 lines]
>
>Banty
Anne Rogers - 27 May 2008 20:36 GMT
> A trait can "skip a generation" only if it's a autosomal recessive and you
> happen to be someone with the same recessive gene.  But I don't think allergies
> are so simple as that.  It's a complex interaction between an inherited
> propensity and environmental exposures as far as I understand it.

Though with variability of expression you can get a dominant gene
passed through the generations, but only some be diagnosed with
whatever disorder it causes, then with current understanding of
genetics find that other family members have the gene, but don't have
expression such that it was diagnosed, but may find they have some
symptoms that are now explained. I think some limb anomolies are
explained this way, with the exact same gene having some family
members unaffected, some with an anomoly in a single limb and others
with severe anomolies in all four and it's only when the child with
the severe anomoly is born that investigations reveal the genetic
basis. This phenomenon is another explanation for "skipping a
generation" and variability of expression is a feature of pretty much
anything genetic, think of the range of problems a down syndrome child
can have.

When it comes to allergies I don't think anyone really knows, genetics
is in there somewhere, but it's nothing clear cut.

Cheers
Anne
Banty - 27 May 2008 20:55 GMT
>> A trait can "skip a generation" only if it's a autosomal recessive and you=
>
[quoted text clipped - 17 lines]
>anything genetic, think of the range of problems a down syndrome child
>can have.

You're right - connective tissue disorders can be that way.  "Skipping
generations" is apparent depending on how it's epressed and the luck of how it's
expressed in the interleaving generation.

>When it comes to allergies I don't think anyone really knows, genetics
>is in there somewhere, but it's nothing clear cut.

I think allergies is something more complex.

Banty
Welches - 27 May 2008 20:57 GMT
> A trait can "skip a generation" only if it's a autosomal recessive and you
> happen to be someone with the same recessive gene. But I don't think
> allergies
> are so simple as that. It's a complex interaction between an inherited
> propensity and environmental exposures as far as I understand it.

<Though with variability of expression you can get a dominant gene
passed through the generations, but only some be diagnosed with
whatever disorder it causes, then with current understanding of
genetics find that other family members have the gene, but don't have
expression such that it was diagnosed, but may find they have some
symptoms that are now explained. I think some limb anomolies are
explained this way, with the exact same gene having some family
members unaffected, some with an anomoly in a single limb and others
with severe anomolies in all four and it's only when the child with
the severe anomoly is born that investigations reveal the genetic
basis. This phenomenon is another explanation for "skipping a
generation" and variability of expression is a feature of pretty much
anything genetic, think of the range of problems a down syndrome child
can have.>
As a quick side note. Genetics is a relatively rare reason for limb loss.
Debbie (who got bored by someone who wouldn't believe that #2 could be born
without a hand if no one else in the family had the same condition)
Nan - 27 May 2008 15:10 GMT
>Well for those of you living in the states, I hope your Memorial Day
>weekend went better than ours!
[quoted text clipped - 34 lines]
>
>Anyone else ever experience this?

Yes, myself and 2 of my 3 children are allergic to Penicillin.  I
developed the allergy when I was in college, at the age of 19.  My ds
reacted when he was 20 months old and my dd at 2-1/2 years.

You'll have to make sure you inform any medical caretakers that he's
had a reaction so they can stay on the safe side and prescribe other
antibiotics if he ever needs them in the future.

I'm glad he's feeling better!

Nan
Ericka Kammerer - 27 May 2008 19:01 GMT
<snip>
> So the ped checks his ears, and the ear we were treating is fine now,
> but now his other ear & tube are clogged and we need to start treating
> that for infection. So she takes him off the Amoxi and puts him on
> Prelone I believe....

<snip>

> I wish our Ped would have prescribed the steroid first, but I guess
> that's a last ditch alternative.

    If she put him on Prelone, she *did* prescribe a
steroid.  Prelone is a steroid.

Best wishes,
Ericka
Michelle J. Haines - 27 May 2008 20:28 GMT
> Anyone else ever experience this?

Yes, it's call urticaria and is a relatively common allergic reaction.
Steroids are a common way to treat it.

The last ditch effort for life-threatening reactions isn't a steroid,
but Benedryl is usually the first drug of choice if the reaction is mild.

Glad everything worked out OK.

Michelle
Flutist
Anne Rogers - 27 May 2008 21:12 GMT
You'll probably never know, you have a flag now to watch carefully
with all sorts of things, particularly antibiotics.

I'll share one thing that happened to us, which we've never heard of
as a possibility which was DS breaking out in hives purely as a result
of a virus, the spots started very early in the illness, prompting
concerns about chicken pox, but it was obvious within a couple of
hours that it wasn't, when it was clear they were hives. He was
prescribed hydoxyzine, benadryl wasn't suggested, don't know the
background to that.

I think you definitely need to review with your doctor, as Ericka
said, the prelone, if you remembered that right and it wasn't
something different with a similar name is a steroid, plus the
benadryl and stopping the presumed cause, yet he got worse and needed
emergency treatment - which to me says we need to talk about this, if
he's that allergic to something, you need to know what it is and how
to spot early signs of reactions to other things, what treatment to
follow, when to head to the hospital etc. you may even need an epi
pen.

The prelone has an awful lot of treatment roles, but I'm struggling to
see exactly where it comes in the ear infection thing, which it seems
is what you understood it to be for, for the hives, it makes sense,
but that leaves the ear untreated when it may need treating - it will
do something, but it actually suppresses the immune system, which if
the key thing is infection fighting isn't going to be helpful, but it
might be if it's an inflamation and draining issue. If it's not
actually bothering him, then it's not urgent, our pediatrican checks
ears after 2 weeks with things like this.

With what you've been saying about ears and his preferences
surrounding type of milk, I would revisit the cows milk issue, I'm no
expert, but I'd definitely rather deal with no cows milk than
recurrent ear infections, we're back there ourselves right now, after
a year or so clear DDs ears are behaving strangely again, we took her
in because she was behaving unwell with no indicator of ear infection
and it was found her ears were full of fluid but not infected, the
recheck showed one clear and one apparently infected, last time we
were on this rollercoaster we headed to a natropath, which was far
more effective than going to the peds to keep checking and wondering
why they seemed to randomly fill up and why one ear would be clear one
time and another the next. Unfortunately our natropath has moved, so
we need to find another if things aren't clear at the next check. DD
was a bit like your DS in showing preference for non cows milk, to our
knowledge she doesn't have a dairy allergy, but she's done so much
better with soy milk on her cereal, we've kept on with it and just buy
it in bulk from costco.

Cheers
Anne
 
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